Until the beginning of the 19th century, no clear clinical differentiation could be made between typhus and typhoid–two of the major pestilence. Brill-Zinsser disease: Recrudescence of epidemic typhus years after the initial attack. The agent that causes epidemic typhus (Rickettsia prowazekii) remains. Brill-Zinsser disease occurs as a late recrudescence of epidemic typhus. The clinical effect of a newly developed azalide, called azithromycin, against Rickettsia.

Author: Teshakar Gakazahn
Country: Myanmar
Language: English (Spanish)
Genre: Music
Published (Last): 1 October 2012
Pages: 242
PDF File Size: 1.14 Mb
ePub File Size: 7.50 Mb
ISBN: 956-8-55673-732-1
Downloads: 57448
Price: Free* [*Free Regsitration Required]
Uploader: Arasar

Brill-Zinsser disease

In a mouse model of recrudescent typhus, animals treated with doxycycline during primary infection produce significantly reduced levels of rickettsemia after administration of dexamethasone, suggesting brilk appropriately timed treatment with this antibiotic may reduce the risk of later Brill-Zinsser disease [13].

The assay format, buffers, and other reagents were used in accordance with methods previously described [7]. Receive exclusive offers and updates from Oxford Academic. Antimicrobial Photodynamic Therapy with Phenothiazinium Photosensitizers in non-vertebrate model Galleria mellonella infected with Fusarium keratoplasticum and Fusarium moniliforme. Other search option s Alphabetical list.

The patient had been treated zlnsser a subacute rib fracture in March and underwent a myringotomy procedure in April but had been otherwise healthy.


Most of these cases had reported contact prior to illness onset with the southern flying squirrel, Glaucomys volans, which serves as a zoonotic zlnsser for a sylvatic cycle of infection [ 56 ]. Nicholson, Joseph Singleton, Catherine M.

However, other data related to the disease are accessible from the Additional Information menu located at the bottom of this page. Because the patient lived near a goat farm, Q fever and tularemia were considered plausible hypotheses, and oral doxycycline was introduced on March This patient experienced an illness compatible with either acute or recrudescent typhus infection, albeit perhaps more mild than some other cases reported in the literature.

Hospital-onset neonatal sepsis and mortality in low resource settings — will bundles save the day? Enterotoxigenic Enteroinvasive Enterohemorrhagic O The patient denied recent exposure to possible reservoirs or vectors of R. The patient’s typhus infection was confirmed by a significant increase in R.

Orphanet: Brill Zinsser disease

For all other comments, please send your remarks via contact us. We report a case of Brill-Zinsser disease in a patient who was born in Morocco and had no history of epidemic typhus.

Retrieved from ” https: Corticosteroids can trigger recurrence of R. He had most recently traveled to Morocco in Rickettsia felis Flea-borne spotted fever. Pseudomonas aeruginosa Pseudomonas infection Moraxella catarrhalis Acinetobacter baumannii. Epidemic typhus is caused by Rickettsia prowazekii and transmitted by human body lice. Results of tests for IgG antibodies to E.


Journal List Emerg Infect Dis v.

Analysis of risk factors for fatal Rocky Mountain spotted fever: An indirect immunofluorescence assay using a cell culture-derived antigen for the detection of antibodies to the agent of human granulocytic ehrlichiosis.

Chest radiograph results were normal. In contrast, the patient in our report was living in a hygienic environment, and an autochthonous infection is therefore highly unlikely.

Brill-Zinsser Disease in Moroccan Man, France,

In this report, we describe the first case of Brill-Zinsser disease following sylvatic R. Only comments written in English can be processed. He denied any history of hospitalization for a severe febrile illness and any exposure to louse bites.

Ann N Y Acad Sci. Few published data exist about the seroprevalence of R. Amoxicillin was prescribed for a putative diagnosis of acute respiratory infection.